Mykel Williams' Run Defense Prowess Crucial for 49ers Despite ACL Injury

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49ers 2025 11th overall pick Mykel Williams, whose rookie season was cut short by a Week 9 torn ACL, proved crucial for San Francisco's run defense. With him on the field, the 49ers ranked 6th in EPA/play against the run, dropping to 26th after his injury. Williams excelled at setting the edge, boasting an NFL-best average depth of tackle against the run (-0.1 yards) and a 6.2% run stop rate. His health for the 2026 season is paramount for the team.