Christian McCaffrey Ranked Top Fantasy Running Back for Week 10

San Francisco 49ers running back Christian McCaffrey has been identified as the premier fantasy option at his position for Week 10 of the 2025 NFL season. Matthew Berry's fantasy football rankings place McCaffrey as the number one running back in PPR leagues, signaling high expectations for his performance. McCaffrey's consistent production makes him a top-tier asset as the 49ers prepare to face the Rams, solidifying his status as a must-start player.